Diagnostic Value of Nucleolar Organizer Regions (AgNORs) in Brush Biopsies of Suspicious Lesions of the Oral Cavity

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Diagnostic Value of Nucleolar Organizer Regions (AgNORs) in Brush Biopsies of Suspicious Lesions of the Oral Cavity

OBJECTIVE The aim of this retrospective study was to report on the diagnostic accuracy of AgNOR-analysis as an adjunctive diagnostic tool of conventional oral exfoliative cytology taken from suspicious lesions in our clinic. STUDY DESIGN Cytological diagnoses obtained from brush biopsies of macroscopically suspicious lesions of the oral mucosa from 75 patients (final diagnoses: 53 histologica...

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Evaluation of proliferation activity of oral lichen planus and oral lichenoid reactions using quantitative and qualitative analysis of AgNORs (Argyrophilic Nucleolar Organizer Regions)

Bachground & Aims: Oral lichenoid reactions (OLR) and oral lichen planus (OLP) are clinically and histopathologically similar but their therapeutic approach are different. Due to the presence of dysplasia in oral lichen planus which effects prognosis, the aim of study was the evaluation of proliferation activity of OLPs and OLRs and their subtypes. AgNOR technique that is inexpensive and easy...

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Argyrophilic Nucleolar Organizer Regions (AgNORs) as a Proliferative marker in various prostatic lesions

Aims and objectives: 1. To establish the role of AgNOR in differentiating the benign from the premalignant and the malignant lesions of the prostate. 2. To establish the significance of AgNOR count in differentiating the grades of malignancy. Materials and methods: A prospective study was conducted on 197 prostatic lesions from 20112013. Two sections from each case were stained with haematoxyli...

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Diagnostic Value of Proliferatin Index Including MIB1 and Argyrophilic Nucleolar Organizer Regions Proteins in Uterine Smooth Muscle Tumors

  Background and Objectives: Uterine smooth muscle tumors are the most common human neoplasm .They are divided clinically as benign and malignant but there is  another group of  lesions which is difficult to place in these two categories ,so-called smooth  muscle tumors of uncertain malignant potential (STUMP) and differentiation  of these tumors on the basis of H&E staining is impossible . Th...

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Nucleolar Organizer Regions of Oral Epithelial Cells in Crack Cocaine Users

Background: The health risks of crack cocaine smoking on the oral mucosa has not been widely researched and documented. Objective: The purpose of this study was to analyze the proliferative activity of oral epithelial cells exposed to crack cocaine smoke using silver nucleolar organizer region (AgNOR) staining. Methods: Oral smears were collected from clinically normal-appearing buccal mucosa b...

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ژورنال

عنوان ژورنال: Analytical Cellular Pathology

سال: 2003

ISSN: 0921-8912,1878-3651

DOI: 10.1155/2003/647685